Projects within this Research Area will explore the microenvironment’s contribution to tumour growth, metastatic potential, and will devise ways to target it for therapeutic purposes.
The tumour microenvironment is quickly moving into the limelight both as driver and potential target for cancer therapy. The neglect of the role of the tumour microenvironment is largely due to the complexities added by considering not only the cancer cell as therapeutic target but also its habitat. Computational modelling can overcome this hurdle. This work will provide us with a better understanding of the tumour microenvironment and its potential role as a therapeutic target.
Prof Darran O'Connor
Royal College of Surgeons Ireland
Dr. Eva Szegezdi
Celgene Institute for Translational Cancer Research